Why Prioritize the Structure-Based Drug Design Summit – San Diego?

As the drive for smarter, faster, and more efficient drug discovery intensified, leveraging structural insights across proteins, complexes, and multi‑modal targets became more critical than ever. Advances in Cryo‑EM, X-ray crystallography, NMR, HDX‑MS, and AI‑driven modelling enabled researchers to visualize dynamic targets, uncover hidden pockets, and guide the rational design of small molecules, biologics, and complex modalities.

Built by biopharma for biopharma, the Structure-Based Drug Design Summit made its West Coast debut in San Diego this February, bringing together structural biologists, medicinal chemists, computational chemists, and protein engineers. Attendees shared best practices, explored real‑world applications, and learned how to integrate structural and computational insights to optimize candidates, reduce attrition, and accelerate discovery.

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Unmissable Event Highlights 

Integrating the Structural Biology Toolbox

Attendees gained practical strategies for integrating diverse structural and computational methods into cohesive drug design workflows, enabling more accurate decision‑making, faster hit‑to‑lead optimization, and improved candidate selection across small molecules and biologics. Experts from Eli Lilly, Vertex, and others shared real-world approaches that advanced cross‑modal structural integration.
Drive Smarter Optimization

Participants unlocked effective strategies to optimize molecules more intelligently and efficiently by leveraging structural insights from using NMR to reveal dynamic behaviors, to applying structurally guided ADME optimization to mitigate metabolic liabilities. Sanofi, Regeneron, and additional leaders demonstrated how these approaches reduced attrition and advanced more potent, selective, and developable candidates.
Explore Real-World Applications

Industry peers showcased how structure-based drug design is being applied to rationally engineer candidates, translating structural insights into smarter design decisions, improved selectivity, and accelerated discovery outcomes. Case studies from MOMA Therapeutics, Structure Therapeutics, and Foghorn Therapeutics highlighted the practical impact of SBDD across diverse therapeutic modalities.

Explore the 2026 Full Event Guide

  • 50+ Industry Experts in Attendance  
  • 18+ World Class Speakers 
  • 8 Hours of Unrivalled Networking Opportunities    
  • 10+ Brand-New Participating Companies 
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Companies That Attended Include

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Explore the 2026 Agenda

Hear the latest industry breakthroughs and gain exclusive insights during our packed agenda, interactive roundtables, and panel discussions.

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Be part of the hottest conversations with like-minded attendees spanning all stages of drug development and make critical connections during our dedicated networking sessions.