Engineering Functional Biologics with Structure-Based Grafting to Unlock Antibodies to go Beyond Binding & Actively Modulate Biology

  • Explore structure-guided strategies to engineer antibodies and biologics that move beyond passive binding to actively modulate biological pathways
  • Leverage structural insights to optimize stability, specificity, and functionality across complex or traditionally intractable targets
  • Discuss emerging design principles and case studies showcasing functional biologics with enhanced therapeutic potential